PSMF SERIES: Burn Stored Body Fat: The Science Behind Protein-Sparing Modified Fasting: Dr. Brian Mowll

In this episode of the Optimal Protein Podcast, Vanessa is joined by Dr. Brian Mowll for a deep dive into protein-sparing modified fasting, or PSMF, as part of the Friday Protein-Sparing Modified Fasting Series.

Check out the Protein-Sparing Modified Fasting Library at ketogenicgirl.com and use code VANESSA for 20% off.

Dr. Mowll explains the origins of PSMF, how it was first developed in clinical settings to help preserve lean body mass, and why it later became a powerful tool for obesity, metabolic health, and fat loss. Vanessa and Dr. Mowll explore how PSMF compares to water fasting and very low-calorie diets, especially when the goal is fat loss while protecting muscle.

They discuss how strategic energy restriction, optimized protein intake, low carbohydrate intake, and low dietary fat can help the body access stored body fat while maintaining lean mass, metabolic rate, satiety, and ketone production. Dr. Mowll also explains how PSMF may support insulin sensitivity, blood sugar regulation, metabolic flexibility, and long-term weight maintenance when followed by a smart transition plan.

This episode also covers practical implementation, including what to eat on PSMF days, ideal protein targets, how low to take carbs and fats, hunger signals, why some people feel energized, and how to transition out of PSMF to reduce the risk of rebound weight gain.

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Vanessa uses the Tone Device as a proxy for fat loss + autophagy on PSMF days

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📚 Free Resource

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👉 The Keto Reset eBook

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⚠️ Disclaimer

This podcast is for informational purposes only and is not medical or nutritional advice. Always consult your healthcare provider before making dietary or lifestyle changes.