78 – Primodos: The forgotten synthetic hormone scandal

Millions of women were prescribed Primodos as a pregnancy test even though there were concerns that it was associated with many different and often devastating birth defects. More than 60 years later, many of the questions surrounding the drug - which contains synthetic hormones that are still prescribed to women today - remain unanswered.

In this episode, Dr Louise Newson is joined by ProfessorNeil Vargesson, Professor of Developmental Biology at the University of Aberdeen, whose research into Primodos has helped shine a light on one of themost dreadful drug scandals in modern medicine.

Together, they explore how Primodos came to be prescribed, why concerns raised by women were not properly investigated, and why it took 20 years for the drug to be withdrawn. They also discuss what the scandal reveals about the regulation of medicines, the importance of knowing about the difference between synthetic and natural hormones and why this history should never be forgotten.

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